CAPRI (Critical Assessment of Predicted Interactions) experiment is a community-wide effort dedicated to evaluating the current state of methods for prediction of protein complex structure.
The evaluation of results for the last three years, was recently published in Proteins.
Automated protein docking server ClusPro developed by our group was ranked first in the server category for all targets . The summary of the results is shown below. For each predictor group, the table shows the number of acceptable or better predictions, and among those the number of high quality models, indicated by three stars, as well as the number of medium quality solutions, indicated by two stars.
| Server rankings | |
|---|---|
| Server | Top 5 Predictions |
| ClusPro | 10/6** |
| HDOCK | 8/1***/5** |
| HADDOCK | 8/2***/2** |
| LZERD | 8/1***/4** |
| MDOCKPP | 9/1***/3** |
| GalaxyPPDock | 6/4** |
| Swarmdock | 6/1***/1 |
| PYDOCKWEB | 3/1** |
In addition our human group was the top performer in protein-protein docking category . The results for the 10 best-performing groups are provided below for comparison.
| Human predictor rankings | |
|---|---|
| Group | Predictions |
| Kozakov/Vajda | 6/1***/6** |
| Venclovas | 5/2***/3** |
| Seok | 5/1***/4** |
| Pierce | 5/2***/2** |
| Andreani/Guerois | 5/1***/3** |
| Zou | 4/1***/3** |
| Zacharias | 5/1***/2** |
| Kihara | 5/1***/2** |
| Gray | 5/1***/2** |
| Shen | 4/1***/2** |